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Eating Disorders (anorexia/bulemia, hypergymnasia, etc.)
Mental & Emotional Health
Weight Loss

Food May Be Addictive

An international group of researchers has found that food craving activates different brain networks in obese patients than it does in normal weight patients. The team believes that this indicates that the tendency to want food may be “hard-wired” into the brain of overweight patients, becoming a functional brain biomarker.

A release on August 30th 2015 from the European College of Neuropsychopharmacology notes that obesity is one of the most difficult problems facing modern society. Treating obesity is a health priority, but most efforts aside from bariatric surgery have met with little success. In part, this is because the mechanisms associated with the desire to eat are poorly understood. Recently, studies are beginning to suggest that the brain mechanisms underlying obesity may be similar to those in substance addiction, and that treatment methodologies may be approached in the same way as other substance addictions, such as alcohol or drug addiction.

To test this, a group of researchers at the University of Granada, Spain, and Monash University in Australia looked for the functional connectivity differences in brain reward systems of normal-weight and obese individuals.

The researchers gave buffet-style food to 39 obese and 42 normal-weight people. Later, the participants were put into functional MRI brain scanners and shown photographs of the food to stimulate food craving. The functional MRI scans showed that food craving was associated with different brain connectivity, depending on whether the subject was normal-weight or overweight.

The scientists found that in obese people, the stimulus from food craving was associated with a greater connectivity between the dorsal caudate and the somatosensory cortex implicated in reward-based habits and the coding of the energetic value of foods, respectively. However, with normal weight people, food craving was associated with a greater connectivity between different parts of the brain – for example, between the ventral putamen and the orbitofrontal cortex.

The researchers then measured Body Mass Index (BMI) three months afterwards and found that 11% of the weight gain in the obese participants could be predicted by the presence of the increased connectivity between the dorsal caudate and the somatosensory cortex areas of the brain.

The release quotes lead researcher Oren Contreras-Rodríguez as saying,

“There is an ongoing controversy over whether obesity can be called a ‘food addiction’, but in fact there is very little research which shows whether or not this might be true. The findings in our study support the idea that the reward processing following food stimuli in obesity is associated with neural changes similar to those found in substance addiction. This still needs to be viewed as an association between food craving behavior and brain changes, rather than one necessarily causing the other. However, these findings provide potential brain biomarkers which we can use to help manage obesity, for example through pharmacotherapies and brain stimulation techniques that might help control food intake in clinical situations”.