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Overview
Rheumatoid arthritis is an inflammatory disease that causes pain, swelling, stiffness, and loss of function in the joints. It has several special features that make it different from other kinds of arthritis. For example, rheumatoid arthritis generally occurs in a symmetrical pattern. This means that if one knee or hand is involved, the other one is also. The disease often affects the wrist joints and the finger joints closest to the hand. It can also affect other parts of the body besides the joints. In addition, people with the disease may have fatigue, occasional fever, and a general sense of not feeling well (malaise).
Another feature of rheumatoid arthritis is that it varies a lot from person to person. For some people, it lasts only a few months or a year or two and goes away without causing any noticeable damage. Other people have mild or moderate disease, with periods of worsening symptoms, called flares, and periods in which they feel better, called remissions. Still others have severe disease that is active most of the time, lasts for many years, and leads to serious joint damage and disability.
Although rheumatoid arthritis can have serious effects on a person's life and well-being, current treatment strategies -- including pain relief and other medications, a balance between rest and exercise, and patient education and support programs -- allow most people with the disease to lead active and productive lives. In recent years, research has led to a new understanding of rheumatoid arthritis and has increased the likelihood that, in time, researchers can find ways to greatly reduce the impact of this disease.
Summary of Features:
- Tender, warm, swollen joints.
- Symmetrical pattern. For example, if one knee is affected, the other one is also.
- Joint inflammation often affecting the wrist and finger joints closest to the hand; other affected joints can include those of the neck, shoulders, elbows, hips, knees, ankles, and feet.
- Fatigue, occasional fever, a general sense of not feeling well (malaise).
- Pain and stiffness lasting for more than 30 minutes in the morning or after a long rest.
- Symptoms that can last for many years.
- Symptoms in other parts of the body besides the joints.
- Variability of symptoms among people with the disease.
How Rheumatoid Arthritis Develops and Progresses >
This is a publication of the National Institutes of Health, National Institute of Arthritis and Musculoskeletal and Skin Diseases. The NIAMS, a part of the National Institutes of Health (NIH), leads the Federal medical research effort in arthritis and musculoskeletal and skin diseases. The NIAMS supports research and research training throughout the United States as well as on the NIH campus in Bethesda, Maryland, and disseminates health and research information. Additional information and research updates can be found on the NIAMS Web site at http://www.nih.gov/niams/
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