The combination of the antibiotic trimethoprim-sulfamethoxazole, frequently prescribed for urinary tract infections, with the diuretic spironolactone, widely used for heart failure, more than doubles the risk of death for older patients, reports a study published in February 2015 in CMAJ (Canadian Medical Association Journal). A release from CMAJ notes that more than 20 million prescriptions… Continue reading Antibiotic for UTI + Diuretic = Risk of Death in Older Patients