Researchers now know why long-term use of L-DOPA (levodopa), an effective treatment for Parkinison’s disease, causes a problem known as dyskinesia, or excessive movement. Using a new method for manipulating neurons in a mouse model of Parkinson’s, a Columbia University Medical Center (CUMC) research team found that dyskinesia arises when striatonigral neurons become less responsive… Continue reading En Route to Better Treatment of Parkinson’s