Can Ketamine Help Patients with Treatment-Resistant Depression?

Researchers have found that a single, low-dose ketamine infusion was relatively free of side effects for patients with treatment-resistant depression. Elia Acevedo-Diaz, M.D., Carlos Zarate, M.D., and colleagues at the National Institute of Mental Health, part of the National Institutes of Health, reported their findings in the Journal of Affective Disorders. Studies have shown that… Continue reading Can Ketamine Help Patients with Treatment-Resistant Depression?

I Tried Ketamine for Depression

I’ve been treated for major depressive disorder for my entire adult life. I’ve been lucky enough to respond well to medication and, while the disease never went away entirely, I coped pretty well for nearly 20 years. But then researchers discovered that the drug I’d been taking had long term effects on the heart; my… Continue reading I Tried Ketamine for Depression

A Revolutionary Anti-Depressant

The substance ketamine can be an effective anti-depressant, but it hasn’t been used because of its hallucinatory and dissociative side effects. Now, though, a solution may be at hand. Researchers at the University of Maryland School of Medicine (UM SOM) have identified a metabolite of ketamine that quickly reverses depression in mice, but without ketamine’s… Continue reading A Revolutionary Anti-Depressant