A new study from UCLA researchers provides a strategy for finding treatments optimally tailored for women and men to prevent cognitive decline in aging as well as progression of neurodegenerative diseases by leveraging sex differences in the brain. BACKROUND Aging is associated with cognitive decline and brain atrophy. Aging also confers a major risk for… Continue reading UCLA researchers offer roadmap for identifying new neuroprotective treatments by leveraging sex differences
Tag: neurodegenerative diseses
Molecular Chaperones, Aging, and Neurodegenerative Diseases
Aging is the most significant and universal risk factor for developing neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer’s, Parkinson’s, and Huntington’s diseases. This risk increases disproportionately with age, but no one really knows why. Now a team of scientists from Northwestern University, Proteostasis Therapeutics, Inc. and Harvard University has uncovered some clues. The… Continue reading Molecular Chaperones, Aging, and Neurodegenerative Diseases
Surprising Mechanism Behind Neurodegeneration
A research team led by Professor Susan Ackerman, Ph.D. at the Jackson Laboratory in Bar Harbor, Mane has pinpointed a surprising mechanism behind neurodegeneration in mice, one that involves a defect in a key component of the cellular machinery that makes proteins, known as transfer RNA or tRNA.