_ Breast Cancer Subtyping Breast Ca to Identify High Risk Women By article A University of South Florida-led study has refined a personalized approach to breast cancer diagnosis and treatment. A release from the university explains that a method called molecular subtyping can help doctors better determine which of their breast cancer patients are at high risk of getting breast cancer again. This sophisticated genetic profiling of an individual's specific tumor offers an additional resource to help identify patients who would most benefit from chemotherapy and those who would not.
_ Breast Cancer 14 Questions About Your Breast Cancer Diagnosis By article prognosis and medical choices.
_ Breast Cancer Stopping Aggressive Breast Cancer By Jane Farrell article The chance of breast cancer spreading beyond the initial tumor may be decreased by lowering the level of a protein, according to new research. A team of investigators from The Ohio State University found that mice implanted with breast cancer cells without the protein, myoferlin, developed self-contained tumors whose cells did not spread beyond the original site. In contrast, mice implanted with cancer cells containing the protein developed larger, irregular masses and showed signs that cancer cells had invaded the surrounding tissue.
Breast Cancer Possible: A New Treatment for Aggressive Breast Cancer By Jane Farrell article Experts have found a process that fuels triple negative breast cancer, the most aggressive form of the illness, and that could lead to new treatments. The researchers, from the University of Michigan Comprehensive Cancer Center and Georgia Regents University, discovered that a protein that fuels an inflammatory pathway does not turn off in breast cancer. The failure to turn off leads to an increase in cancer stem cells. The protein, SOCS3, is highly expressed in normal cells but until now has been undetectable in triple-negative breast cancer.
_ Breast Cancer New Breast Ca Surgical Guideline By article The Society of Surgical Oncology announced on February 10th 2014 the release of a comprehensive consensus guideline for physicians treating breast cancer that will reduce healthcare costs and improve the course of treatment. Developed in conjunction with the American Society of Radiation Oncology, the guideline outlines an evidence-based surgical treatment path that will save patients from unnecessary surgery.
Breast Cancer The Mammogram Controversy Continues By Jane Farrell article Annual mammograms for women aged 40-59 don’t reduce the death rate from breast cancer, according to a new study. The study, published on bmj.com, also said that 22 percent of breast cancers detected via mammogram were over-diagnosed—meaning that the cancers that were found were ones that would not cause symptoms or death. The findings are fueling an ongoing debate about the benefits of mammograms.
_ Breast Cancer Best Tx for Advanced Breast Cancer By article The first large-scale study of whole-genome testing is aimed at identifying the best treatment for women with advanced breast cancer.
_ Breast Cancer Biennial Mammograms Just as Good as Annual Ones? By Jane Farrell article The adoption of guidelines calling for mammograms every two years for women age 50 to 75 would yield effective breast screenings and save the United States $4.3 billion a year in health care costs, a new study said.
Breast Cancer Running Trumps Walking for Breast Cancer Survival By article Previous studies have shown that breast cancer survivors who meet the current exercise recommendations of 2.5 hours of moderate intensity physical activity per week are at 25% lower risk for dying from breast cancer. Now research from the U.S. Department of Energy's Lawrence Berkeley National Laboratory and reported in the International Journal of Cancer suggests that exceeding the recommendations may provide greater protection, and that running may be better than walking.
_ Breast Cancer New Way to Image Dense Breasts By article Dartmouth engineers and radiologists are developing new approaches for an emerging technique called MRI with near-infrared spectroscopy (NIRS) to image dense breasts for abnormalities. The study will appear in the February 2014 issue of the journal Academic Radiology.