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Breast Cancer

Exposure To Nighttime Light Could Be Dangerous for Breast-Cancer Patients

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The breast-cancer drug tamoxifen is useless if a patient is exposed to even dim overnight light, according to a new study. But it can become effective during the same period in combination with the hormone melatonin. Researchers from Tulane University School of Medicine published the study in the journal Cancer Research. It is the first study to show that melatonin, which regulates sleep and wake cycles, is essential to tamoxifenΓÇÖs success in treating breast cancer. But melatonin doesnΓÇÖt work if itΓÇÖs shut off by exposure to light at night.

Women's Health and Wellness

Hysterectomy With Morcellation Poses Cancer Risk

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Among women undergoing a minimally invasive hysterectomy using electric power morcellation, uterine cancers were present in 27 per 10,000 women at the time of the procedure, according to a study published July 22nd 2014 by JAMA. There has been concern that this procedure, in which the uterus is fragmented into smaller pieces, may result in the spread of undetected malignancies.

A New Cancer Treatment for Dogs

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A cancer therapy that was until now only available for humans has been developed for dogs. Scientists from the Messerli Research Institute of the Vetmeduni Vienna, the Medical University of Vienna, and the University of Vienna have developed a way to use cancer immunotherapy on dogs. Almost half of dogs ten years or older develop cancer.

Breast Cancer

Some Cancers Respond to Anti-Inflammatory Drugs

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Research done at the Washington University School of Medicine in St. Louis raises the possibility that some cancer patients with aggressive tumors may benefit from a class of anti-inflammatory drugs used to treat rheumatoid arthritis. The investigators published their findings in a 2014 issue of the journal Cell Reports.

Breast Cancer

A Possible Link Between Carbohydrates and Breast Cancer

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Limiting carbohydrate intake could reduce the risk of one type of breast cancer, researchers have found. The findings, published in the journal Cancer Epidemiology Biomarkers & Prevention, focused on the cancer whose tumor tissue has the IGF-1 receptor. "There is a growing body of research demonstrating associations between obesity, diabetes, and cancer risk," said lead author Jennifer A. Emond, an instructor in the Department of Community and Family Medicine at the Geisel School of Medicine at Dartmouth College.

Delivering a Drug ΓÇ£CocktailΓÇ¥ to Cancer Cells

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Biomedical engineering researchers at North Carolina State University and the University of North Carolina at Chapel Hill have developed daisy-shaped, nanoscale structures that are made predominantly of anti-cancer drugs and are capable of introducing a "cocktail" of multiple drugs into cancer cells.

Breast Cancer

Hope for Beating HER2-Positive Breast Cancer

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Scientists at Cold Spring Harbor Laboratory on Lonf Island in New York report on May 18th 2014 a discovery that they hope will lead to the development of a powerful new way of treating an aggressive form of breast cancer commonly called "HER2-positive".

New Cancer Tx Raises Blood Pressure

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The upside of new cancer therapies that block vascular endothelial growth factor (VEGF) signaling is that these agents have improved the outlook for patients with some cancers and are now used as a first line therapy for some tumors. However the downside is that almost 100% of patients who take VEGF inhibitors (VEGFIs) develop high blood pressure, and a subset develops severe hypertension. That is the finding of a study done at the Institute of Cardiovascular and Medical Sciences, University of Glasgow.

Breast Cancer

Study: Chemotherapy Not Always Best for Breast Cancer

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Although many women with early-stage breast cancer are getting chemotherapy, the ones that decide against it appear to be more empowered about making a good decision, new research indicates. The current guidelines for treating cancer that hasn’t spread to the lymph nodes or other parts of the body have led to thousands of women receiving chemotherapy without benefiting from it.

Targeting Blood Vessels That Keep Cancer Alive

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Researchers from at the University of Pennsylvania are using a DNA vaccine to kill cancer, not by attacking tumor cells but targeting the blood vessels that keep them alive. The vaccine also indirectly creates an immune response to the tumor itself, which amplifies the attack because of a phenomenon called epitope spreading. The results of the study were published in April 2014 in the Journal of Clinical Investigation.

Does Memory Decline Lower Cancer Risk?

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Having some senior moments? The upside is that you may be at a lower risk for dying of cancer. A study done at the University Hospital in Madrid and in the April 9th 2014 online issue of Neurology, the medical journal of the American Academy of Neurology, found that older people who are starting to have memory and thinking problems but do not yet have dementia may have a lower risk of dying from cancer than people who have no memory and thinking problems.  

Breast Cancer

Hope For Treating A Deadly Breast-Cancer Gene

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Researchers have discovered that a gene, previously not linked to breast cancer, plays a central role in the growth of triple negative breast cancer. Targeting that gene, the research indicates, could lead to a new approach for treating that form of the disease.  Triple negative breast cancer, which accounts for 20 percent of all breast cancer cases, often has few treatment options.

Androgen Deprivation Therapy Ineffective For Early-Stage Prostate Cancer

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Men who got androgen deprivation therapy as the primary treatment in the early stages of prostate cancer didn’t live any longer than those who got no treatment at all, a study shows. The researchers say that this conclusion, along with the risk of serious side effects such as heart disease and diabetes, “mitigates against any clinical or policy rationale for use of primary androgen deprivation therapy [PADT] in these men.”

A Sharp Drop in Deaths From Colon Cancer

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Colon cancer screenings have led to a 30 percent drop in cases for people aged 50 and older, the American Cancer Society reports. Death rates have also declined. The drop was measured over the last ten years. The researchers who conducted the study said the decrease was due to more people getting recommended screening tests. And even more deaths could be avoided if everyone got their screening tests on time.

Men's Health

A Molecule That Could Cure Prostate Cancer

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Researchers from the University of Texas Southwestern Medical Center may have discovered a way to potentially shut down the growth of prostate cancer cells. Dr. Ralf Kittler, Assistant Professor of Pharmacology, studies ERG, a protein that facilitates the transformation of normal prostate cells into cancer cells. He and fellow investigators found that a molecule called WP1130 can ultimately lead to the destruction of ERG. “We now have a target that we could potentially exploit to develop a drug for treatment,” Kittler said in a statement.

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