_ Overactive Bladder (OAB) & Incontinence Urinary Health Dr. Marie's Help for Incontinence By Sondra Forsyth article A 2008 article in the New England Journal of Medicinearticle revealed that 25 percent of perimenopausal women and 40 percent of postmenopausal women report leakage of urine. ThirdAge medical expert Marie Savard, M.D., author of "Ask Dr. Marie," says that the main causes of this annoying condition are decreased estrogen levels and aging pelvic muscles that are losing strength. She adds that obesity can exacerbate the condition, as can asthma, diabetes, a chronic cough, and medications such as diuretics, antihistamines, and antidepressants.