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How to Fight Prediabetes

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Type 2 diabetes is one of the most serious chronic illnesses in existence; it puts people at risk for everything from heart and kidney disease to amputation of limbs. According to the American Diabetes Association (ADA), it is shockingly widespread 29.1 million Americans have the illness. And the ADA estimates that 86 million more Americans have prediabetes, a condition that indicates a high risk of developing the illness. Here, from the federal National Diabetes Information Clearinghouse and the ADA, is what you need to know about prediabetes:

Obesity

Toward New TX for Obesity & Diabetes

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Research done at the University of Texas Southwestern Medical Center could lead to new therapies to treat obesity and diabetes. The team found that a protein that controls when genes are switched on or off plays a key role in specific areas of the brain to regulate metabolism. The transcription factor involved ΓÇô spliced X-box binding protein 1 (Xbp1s) ΓÇô appears to influence the body's sensitivity to insulin and leptin signaling.

Rosemary & Oregano Fight Diabetes

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The popular culinary herbs oregano and rosemary are packed with healthful compounds, and now lab tests show they could work in much the same way as prescription anti-diabetic medication, scientists report. In their study published in July 2014 in the Journal of Agricultural and Food Chemistry, Elvira Gonzalez de Mejia and colleagues found that the way the herbs are grown makes a difference, and they also identified which compounds contribute the most to this promising trait.

New Clue to Development of Diabetes

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Researchers have discovered a mechanism that can eliminate excess quantities of a harmful protein in people with Type 2 diabetes. The discovery sheds light on the accumulation of the protein called islet amyloid polypeptide, or IAPP. That accumulation is linked to the loss of pancreatic beta cells that produce insulin. Researchers from UCLA appear to have found why that happens.

Safe Traveling with Diabetes

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Getting out of your routine is part of the fun of vacation and traveling. But donΓÇÖt forget your medications and your care routine, especially if you have diabetes, the Centers for Disease Control (CDC) says. Experts at the federal agency, part of the National Institutes of health, say that travel factors such as meals away from home, a change in physical activity, and different time zones can affect your management of your conditions.

How Obesity-Induced Diabetes Begins

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Scientists from the University of California, San Diego School of Medicine have discovered the sequence of early cellular responses that can ultimately lead to obesity-induced insulin resistance and diabetes. The cells respond, the investigators said, to a high-fat diet. ΓÇ£WeΓÇÖve described the etiology [cause] of obesity-related diabetes. WeΓÇÖve pinpointed the steps, the way the whole thing happens,ΓÇ¥ said Jerrold M. Olefsky, MD, associate dean for Scientific Affairs and Distinguished Professor of Medicine at UC San Diego.

The Subtle Signs of Diabetes

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FROM THE MAYO CLINIC Early symptoms of diabetes, especially type 2 diabetes, can be subtle or seemingly harmless ΓÇö if you have symptoms at all. Over time, however, you may develop diabetes complications, even if you haven't had diabetes symptoms. In the United States alone, nearly 7 million people have undiagnosed diabetes, according to the American Diabetes Association. But you don't need to become a statistic. Understanding possible diabetes symptoms can lead to early diagnosis and treatment ΓÇö and a lifetime of better health.

6 Tips for Overcoming Diabetes Burnout

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By Ginger Vieira Diabetes isn’t easy, and having to prick your finger day in and day out to check your blood sugar can be grating. Even though this task takes up about a combined 120 seconds of our day, it’s a tedious responsibility that comes with “good” or “bad” news depending on whatever our blood sugar is. After a while, who could blame you for being sick of it, for forgetting to do it, or for wanting to forget you have diabetes altogether?

Detecting Diabetes Eye Damage Early

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Indiana University researchers have detected new early-warning signs of the potential loss of sight associated with diabetes. This discovery could have far-reaching implications for the diagnosis and treatment of diabetic retinopathy, potentially impacting the care of over 25 million Americans. The study was published in April 2014 in the journal Biomedical Optics Express.

Diabetes and Mount Everest

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Using the high altitude of Mount Everest, scientists have expanded our understanding of how low oxygen levels in the body are linked with Type II diabetes. The research, led by investigators from the University of Southampton in the UK, was published in the journal PLOS One.  

Startling Findings About Diabetes Tx

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Scientists thought they basically knew how the most common drugs used to treat type 2 diabetes worked, but a new study from the Florida campus of The Scripps Research Institute (TSRI) reveals unexpected new aspects of the process. These findings could eventually lead to more potent anti-diabetic drugs with fewer serious side effects. The study was published in the April 7th 2014 issue of the journal Nature Communications.

What You May Not Know About Preventing Heart Attacks, Strokes, and Diabetes

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By Bradley Bale MD and Amy Doneen ARNP with Lisa Collier Cool Have you ever wondered why someone could feel perfectly fine and then minutes later have a massive heart attack or stroke that either kills the person or causes a life-long disability? Even more challenging is the concept that some people can go in for a full medical exam, including cholesterol and blood pressure check and a stress test, and be told they are fine only to drop dead of a heart attack days or weeks later. 

Women's Health and Wellness

Diabetes & Stroke Linked for Women

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New research done at at the Pennington Biomedical Research Center in Baton Rouge, Louisiana and published in the journal Diabetologia shows that diabetes in women is associated with an increased risk of stroke. Yet the data do not show the same association among men. Also, the researchers found the risk of stroke among diabetic women was substantially raised for women aged 55 years and over compared with younger women.

Diabetes: ΓÇ£Lend a HandΓÇ¥ Prioritizes Goals

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The "lend a hand " illustration that accompanies this article shows an open palm with the five major forms of diabetes interventions are arranged in descending order of importance from thumb to little finger as follows: smoking cessation, blood pressure control, metformin therapy, lipid reduction, and glucose control.

Racial Disparities in Type 2 Diabetes

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Two surprising risk factors – diminished lung function and low serum potassium levels - appear to have nearly the same impact as obesity in explaining why African-Americans are disproportionately prone to developing type 2 diabetes, according to research done at Duke University Medicine and published in the February 2014 print edition of the Journal of General Internal Medicine. The finding points to potential new avenues for developing treatments.  

Diabetes: 7 New Genetic Regions

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Seven new genetic regions associated with type 2 diabetes have been identified in the largest study to date of the genetic basis of the disease. DNA data was brought together from more than 48,000 patients and 139,000 healthy controls from four different ethnic groups. The research was conducted by an international consortium of investigators from 20 countries on four continents, co-led by investigators from Oxford University's Wellcome Trust Centre for Human Genetics. The study is published in the February 2014 issue of journal Nature Genetics.

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