_ A New Kind of Drug for Alzheimer's? By Jane Farrell article Researchers have discovered a new drug target to fight AlzheimerΓÇÖs, and the finding could lead to a new diagnostic tool as well. Earlier drugs have long targeted the amyloid protein called plaques, which can cause neurons in the brain to die. But Penn State University researchers have found that another substance, a neurotransmitter known as GABA, could also be implicated in the development of AlzheimerΓÇÖs.
_ Depression LInked to Quicker Progression of Alzheimer's By Jane Farrell article Late-life depression could be a major risk factor for developing AlzheimerΓÇÖs more quickly than those who arenΓÇÖt depressed. The finding was presented at the annual meeting of the Society of Nuclear Medicine and Molecular Imaging. ΓÇ£Our results clearly indicate that mild cognitively impaired subjects with depressive symptoms suffer from elevated amyloid-levels when compared with non-depressed individuals,ΓÇ¥ said the studyΓÇÖs principal scientist Axel Rominger, MD, from the department of nuclear medicine at the University of Munich in Germany.
_ Gene Variants Identified As Source of Deadly Illnesses By Jane Farrell article Two widely carried gene variants that lead to longer chromosome caps also increase the risk of developing the brain cancers known as gliomas. The researchers, led by scientists from the University of California, San Francisco, found that the variants lead to longer telomeres, the caps on chromosome ends that are thought to protect cells from aging. The genetic variants, in two genes known as TERT and TERC, are respectively carried by 51 percent and 72 percent of the general population.
New Gene Involved in Parkinson's Disease By Sondra Forsyth article Researchers at the University of California, Los Angeles have identified a new gene involved in Parkinson's disease, a finding that may one day provide a target for a new drug to prevent and potentially even cure the debilitating neurological disorder. The five-year study appears June 4th , 2014 in eLife, a new, open access scientific journal for groundbreaking biomedical and life research sponsored by the Howard Hughes Medical Institute (United States), the Wellcome Trust (United Kingdom) and Max Plank Institutes (Germany).
_ Differentiating Among Dementia Diseases By Sondra Forsyth article Not all cognitive decline is Alzheimer’s. Now a new diagnostic tool developed at the University of Eastern Finland helps clinicians differentiate among Alzheimer's disease, frontotemporal dementia, and mild cognitive impairment. The method, devised by Miguel Ángel Muñoz Ruiz MD and explained in articles in PloS ONE and Journal of Alzheimer's Disease, consists of a Disease State Index combining data from multiple sources, and of a Disease State Fingerprint showing the findings in a visual format.
_ Midlife High BP May Affect Memory in Old Age By Sondra Forsyth article New research suggests that high blood pressure in middle age plays a critical role in whether blood pressure in old age may affect memory and thinking. The study is published in the June 4th 2014 online issue of Neurology, the medical journal of the American Academy of Neurology.
_ Breakthrough in Fighting Skin & Lung Cancers By Sondra Forsyth article Researchers at UCLAΓÇÖs Jonsson Comprehensive Cancer Center are reporting promising treatment milestones for patients with deadly skin and lung cancers who are being treated with an experimental drug called MK-3475.
_ 5 Facts To Know About Depression By Jane Farrell article Depression, a serious and potentially life-threatening condition, affects 14.8 million American adults, according to the federal Centers for Disease Control (CDC). The percentage of seniors who have the disorder varies from less than 1 percent to 5 percent, the CDC says. But the percentage rises sharply to 11.5 percent among elderly hospital patients to 13.5 percent among those who have home health care. The condition is complex and multi-faceted, encompassing both physical and mental symptoms, and for a patient or caregiver itΓÇÖs essential to know as much as possible about it.
_ Memory Restoration May Be Possible By Jane Farrell article Researchers are now able to reactivate a memory that has vanished from the brain. A study from the University of California, San Diego School of Medicine, detailed how researchers removed a memory from the brain of rat subjects and then restored it.
_ Good Looks and Pleasant Scents By Jane Farrell article Want people to think youΓÇÖre even prettier than you are? Spray on some perfume, or have some flowers in the vicinity. New research shows that womenΓÇÖs faces get a higher attractiveness rating when pleasant odors are in the vicinity. However, the odors didnΓÇÖt affect peopleΓÇÖs evaluation of age. ΓÇ£Odor pleasantness and facial attractiveness integrate into one joint emotional evaluation,ΓÇ¥ said lead author Janina Seubert, PhD, a cognitive neuroscientist who was a postdoctoral fellow at Monell Chemical Senses Center, in Philadelphia, at the time the research was conducted.
Bug Off: Insect Repellent Awareness Day By Jane Farrell article Tuesday, June 3rd 2014 is the first ever Insect Repellent Awareness Day, launched in the UK by launched by scientists at the London School of Hygiene & Tropical Medicine to highlight the importance of using repellents, especially when travelling to tropical countries where insects can spread disease. The campaign also aims to dispel the many myths surrounding insect repellents and other ways to protect against bites.
Aging Well Seniors Have Roomies, Too By Jane Farrell article By Judy Santamaria, MSPH Most of us know that loneliness isn't good for us -- but as we age, many of us find our circle of friends and family diminishing in size for various reasons. Sometimes consciously, sometimes not, loneliness can creep in, and begin to affect our spirits in a less-than-healthy way. Recently, I've been hearing about some really interesting ways seniors are stacking the deck in their own favor to combat loneliness associated with aging, and I wanted to share a few of them with you here.
_ Healthy Diet & Nutrition Update on Leptin & Appetite Control By Jane Farrell article Twenty years ago, scientists found that the hormone leptin regulates metabolism, appetite, and weight through brain cells called neurons. Now Yale School of Medicine researchers have discovered that the hormone also acts on glial cells in the brain cells to control appetite. The study, published in the June st 2014 issue of Nature Neuroscience, could lead to development of treatments for metabolic disorders such as obesity and diabetes.
The "Alzheimer's Movie" By blog There are hundreds and hundreds of books on the topic of the AlzheimerΓÇÖs disease, the brain and brain health. But there are few novels that feature the disease as its central plot. One single novel stands out. ΓÇ£Still AliceΓÇ¥ is the best-selling book written by first-time author Lisa Genova, a Harvard-educated neuroscientist. Published in 2009, ΓÇ£Still AliceΓÇ¥ is a moving, compelling and heart-breaking work of fiction that totally captures the experience of early-onset AlzheimerΓÇÖs. If you have not read it, I highly recommend you do. This book will move you to tears.
Weight Loss When to Start a Diet By Sondra Forsyth article By Sondra Forsyth Bathing suit weather is back and you may be wishing you had stuck your New YearΓÇÖs Resolution to lose some weight. DonΓÇÖt be discouraged! Here are some strategies for getting kicking off a diet and sticking with it: PICK A START DATE THAT HAS POSITIVE SIGNIFICANCE FOR YOU
_ Delivering a Drug ΓÇ£CocktailΓÇ¥ to Cancer Cells By Jane Farrell article Biomedical engineering researchers at North Carolina State University and the University of North Carolina at Chapel Hill have developed daisy-shaped, nanoscale structures that are made predominantly of anti-cancer drugs and are capable of introducing a "cocktail" of multiple drugs into cancer cells.
Pain Management 6 Myths About Painkillers By Jane Farrell article By Richard W. Rosenquist, MD , Chairman of Pain Management at Cleveland Clinic When it comes to prescription pain medications, thereΓÇÖs a lot of misinformation out there.
_ Exercise How to Get the Most Out of Exercise at Home By Jane Farrell article By Soriyaa Bawa Whether you exercise at home or at the gym, some form of physical activity is essential for aging well. We know of the infinite benefits that exercise at home has on physical health, but more and more findings have been emerging as of late to support the idea that exercise at home is just as important for mental health.