A Better Tool for Tracking MS By article Imaging scientists at Western University's Robarts Research Institute in London and Canada have developed a better way to track the progression of Multiple Sclerosis (MS) from its earliest stages. Led by Ravi Menon, PhD, the researchers used what's called "Quantitative Susceptibility (QS) Magnetic Resonance Imaging (MRI)," to measure damage in specific areas of the brain which the study showed to be common to all patients. The findings were published in advance online in May 2014 in Radiology.
_ If You're Considering A Cochlear Implant By Jane Farrell article Cochlear implants ΓÇö which bypass damaged or nonworking parts of the inner ear ΓÇö can improve hearing for anyone with hearing loss that canΓÇÖt be adequately managed with conventional hearing aids. Cochlear implants are electronic devices that convert acoustic sounds into electrical pulses that stimulate the auditory nerve directly. The pulses, which are organized like the keys of a piano, are delivered to points along the inner ear. The pulses stimulate the auditory cells that represent the various speech sounds.
_ Stroke A Longer Window for Treating Stroke? By Jane Farrell article There is an urgent need for developing new drugs that can alleviate the harmful effects of a stroke because current treatment possibilities using thrombolysis are limited to the first hours following a stroke. To that end, researchers at Lund University in Sweden are studying brain cells known as pericytes. The team discovered in 2012 that pericytes can for new cells. According to a release from the university, the 2014 research shows for the first time that pericytes are directly involved in the reaction of the brain tissue after stroke.
_ A Step Forward In the Fight Against Alzheimer's By Jane Farrell article Researchers have developed a molecular compound that reversed the symptoms of AlzheimerΓÇÖs in mice. The compound also reduced inflammation of the brain. The compound, antisense oligonucleotide (OL-1), ΓÇ£reversed learning and memory deficits and brain inflammation in mice that are genetically engineered to model AlzheimerΓÇÖs disease,ΓÇ¥ said Susan Farr, Ph.D., research professor of geriatrics at Saint Louis University. The findings were published in the Journal of AlzheimerΓÇÖs Disease.
Sleep Health 7 Hidden Causes of Fatigue By Jane Farrell article From the Cleveland Clinic Fatigue can signal anemia, diabetes, hypothyroidism or hepatitis C. But once your doctor rules out major medical causes of fatigue, it’s time to consider hidden ones. “We look for the less obvious roots of fatigue — that’s our job,” says Tanya Edwards, MD, Medical Director of Cleveland Clinic’s Center for Integrative Medicine. Hidden causes include: 1. A junk food diet
_ Clot-Busting Can Help or Harm Stroke Patients By article Johns Hopkins researchers say they have developed a technique that can predict with 95 percent accuracy which stroke victims will benefit from intravenous, clot-busting drugs and which will suffer dangerous and potentially lethal bleeding in the brain. Reporting online May 15th 2014 in the journal Stroke, the Johns Hopkins team says these predictions were made possible by applying a new method they developed that uses standard magnetic resonance imaging (MRI) scans to measures damage to the blood-brain barrier that protects the brain from drug exposure.
_ Healthy Diet & Nutrition The Importance of Prebiotics and Probiotics By Sondra Forsyth article By Sondra Forsyth Both prebiotics and probiotics are essential components of a healthy diet. Prebiotics are indigestible carbohydrates that act as food for probiotics, which contain live bacteria. Together, they help promote the growth of the good bac- teria in your intestines and maintain your gut’s ecosystem. When a food contains both substances, it is called synbiotic: a synergistic combination of the two. Prebiotics
Antidepressant May Slow Alzheimer's By article Citalopram (brandname Celexa), a commonly prescribed antidepressant, can reduce production of the main ingredient in Alzheimer's brain plaques. That is the finding research done at Washington University School of Medicine in St. Louis and the University of Pennsylvania. The study was published May 14th 2014 in Science Translational Medicine.
_ Protein Fragments and Alzheimer's By Jane Farrell article Two newly discovered protein fragments may lead to drugs that will better treat Alzheimer’s disease. In a study published in the Journal of Alzheimer’s Disease, Prof. Illana Gozes, of Tel Aviv University’s Sagol School of Neuroscience, said that investigators had already focused on a protein called NAP, which is essential for brain formation. Now, they have found similar protein fragments. In their study, investigators looked at the effect of the fragments on mice with symptoms similar to thse of Alzheimer’s.
_ Mental & Emotional Health May Is Mental Health Month: WhereΓÇÖs Your Sanity? By article By Dr. Claudia LuizΓÇ¿ΓÇ¿ Everybody is overwhelmed and nobody is afraid to talk about it. Historically speaking, we are more sophisticated than ever emotionally; we are highly aware of what we feel, and we can talk about it. If we don’t feel better, it’s only because our methods for dealing with what we feel are still so antiquated. It’s just the same-old, same-old: try to be better, get inspired to change. But it doesn’t’ work. ΓÇ¿ ΓÇ¿
Tools To Take Charge Of Your Cancer Survivorship By blog Most major cancer centers today offer a survivor care plan to organize your diagnosis, treatment and follow-up plan. It will soon be a standard of care to provide treatment summaries and survivorship care plans to all cancer patients. The primary components of a plan include: Diagnostic tests performed and results; including tumor site, stage, grade and other biomarker information.
The Life-or-Death Molecule By Jane Farrell article Researchers have zeroed in on a molecule that’s involved in cell death, a discovery that could lead to better treatment for inflammatory illnesses such as psoriasis, rheumatoid arthritis and Crohn’s disease. The investigators found that a previously identified molecule, RIPK1, inhibits necroptosis (cell death), which is implicated in inflammatory conditions. Paradoxically, RIPK1 is also responsible for initiating cell death.
_ AFib = Dementia Risk If Meds Are Out of Range By article A study done by researchers at the Intermountain Medical Center Heart Institute in Salt Lake City has found that atrial fibrillation patients who are on blood thinning medications are at higher risk of developing dementia if their doses are not in the optimal recommended range. The findings presented at the 2014 Annual Heart Rhythm Society Scientific Session on Friday, May 9th, 2014 in San Francisco.
_ Free Radicals May Be Good Guys After All By article Free radicals, the sometimes-toxic molecules produced by our bodies as we process oxygen, have received a lot of bad press claiming that they are they are the culprits behind aging. Yet a number of studies have found evidence that the opposite may be true. Most recently, researchers at McGill University in Montreal have shown that free radicals promote longevity in the roundworm C. elegans. Surprisingly, the team discovered that free radicals – also known as oxidants – act on a molecular mechanism that, in other circumstances, tells a cell to kill itself.
"Energy Source" Implicated in Dementia By Jane Farrell article Researchers now know that a specific energy source is crucial to cells that maintain cognitive function. That discovery could lead to a better understanding of the cognitive decline in illnesses such as Alzheimer’s and multiple sclerosis. The source, NAD (nicotinamide adenine dinucleotide), is a molecule that harvests energy from nutrients in food and converts into a usable form for cells.
Why Seniors Get Addicted to Drugs By Jane Farrell article For older people who have chronic conditions or find themselves in a lot of pain temporarily, medicine can be a godsend that vastly improves quality of life. But senior citizens may find it all too easy to abuse prescription and over-the-counter drugs. Just because such medicines are bought in drugstores rather than on the street, say, doesn’t mean that they are any less dangerous. Overuse of drugs can lead to additional health problems, family problems, and even fatalities.
_ A Possible Cause of Age-Related Memory Decline By article Research done at the Lieber Institute for Brain Development in Baltimore, MD and the National Institute of Mental Health suggests that one cause of age-related memory decline is a protein called KIBRA and the gene responsible for its production is WWC1. KIBRA is known to play a role in human memory. The study was published in the May 2014 issue of Biological Psychiatry.