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Obesity

Clue to Curbing Obesity

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Preventing weight gain, obesity, and ultimately diabetes could be as simple as keeping a nuclear receptor from being activated in a small part of the brain, according to a study done by Yale School of Medicine researchers andp ublished in the August 1st 2014 issue of The Journal of Clinical Investigation (JCI).

Obesity

Toward New TX for Obesity & Diabetes

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Research done at the University of Texas Southwestern Medical Center could lead to new therapies to treat obesity and diabetes. The team found that a protein that controls when genes are switched on or off plays a key role in specific areas of the brain to regulate metabolism. The transcription factor involved ΓÇô spliced X-box binding protein 1 (Xbp1s) ΓÇô appears to influence the body's sensitivity to insulin and leptin signaling.

Estrogen May Affect Male Obesity

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An imbalance of female hormones may contributing to obesity among men in Western nations. In a paper published in the journal PLOS ONE, researchers from the University of Adelaide's School of Medical Sciences, in Australia, said that part of the massive weight gain among men could be linked with exposure to substances containing estrogen. "Hormonally driven weight gain occurs more significantly in females than in males, and this is very clear when we look at the rates of obesity in the developing world," said medical student James Grantham, co-author of the study.

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